Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24526487 | 1.00 | HCAR1 (0.50) | HCAR1HPGDSMN1; SMN2HTR7L3MBTL1 | |
| SCHEMBL5565349 | 0.88 | CES2 (0.50) | HPGDSMN1; SMN2HTR7L3MBTL1HSD17B3 | |
| SCHEMBL7878110 | 0.83 | TPMT (0.59) | HCAR1HPGDSMN1; SMN2L3MBTL1HSD17B3 | |
| SCHEMBL24526486 | 0.81 | MEN1 (0.46) | HPGDSMN1; SMN2HTR7L3MBTL1HSD17B3 | |
| SCHEMBL336433 | 0.79 | HCAR1 (0.73) | HCAR1HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL6175693 | 0.79 | HCAR1 (0.55) | HCAR1HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2293148 | 0.77 | HCAR1 (0.70) | HCAR1HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL28429598 | 0.76 | HPGD (0.55) | HPGDSMN1; SMN2L3MBTL1HSD17B3KMT2A | |
| SCHEMBL157714 | 0.75 | HCAR1 (0.73) | HCAR1HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| Butane SCHEMBL27893070 | 0.75 | TPMT (0.55) | HCAR1HPGDSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |