Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | DHFR | P00374 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.66 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130520 | 1.00 | ACMSD (0.66) | ACMSDCA1CA2MEN1KMT2A | |
| SCHEMBL27405095 | 0.98 | ACMSD (0.64) | ACMSDCA1CA2MEN1KMT2A | |
| Phosphoric Acid SCHEMBL31026334 | 0.92 | ACMSD (0.58) | ACMSDCA1CA2MEN1KMT2A | |
| Phosphoric Acid SCHEMBL8776062 | 0.92 | ACMSD (0.58) | ACMSDCA1CA2MEN1KMT2A | |
| Phosphoric Acid SCHEMBL31026333 | 0.92 | ACMSD (0.58) | ACMSDCA1CA2MEN1KMT2A | |
| SCHEMBL27382597 | 0.87 | MEN1 (0.54) | ACMSDCA1CA2MEN1KMT2A | |
| SCHEMBL330405 | 0.84 | ACMSD (0.72) | ACMSDCA1CA2MEN1KMT2A | |
| SCHEMBL3695268 | 0.82 | ACMSD (0.70) | ACMSDCA1CA2MEN1KMT2A | |
| SCHEMBL3690106 | 0.82 | ACMSD (0.70) | ACMSDCA1CA2MEN1KMT2A | |
| SCHEMBL188203 | 0.82 | ALDH1A1 (0.61) | ACMSDCA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | disclosed |
| EP-4337203-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | Syndax Pharmaceuticals, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-3541368-B1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | US HEALTH (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022241265-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | SYNDAX PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | THE USA, AS REPRESENTED BY THE SECRETARY, DHHS (US) | 2022-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | PUF60, PBRM1, PCBP1 | ACMSD 1364/4885CA1 553/4885CA2 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.