SCHEMBL29759663

SCHEMBL29759663

O=C(O)c1cc(-c2ccc(-c3ccccc3)cc2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 10/20 1.00
MCL1 Q07820 8/20 1.00
HNF4A P41235 2/20 1.00
DHFR P00374 1/20 1.00
GSTA1 P08263 1/20 0.70
LCK P06239 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23143193 1.00 ACMSD (1.00) ACMSDMCL1HNF4ADHFRGSTA1
SCHEMBL330602 1.00 ACMSD (1.00) ACMSDMCL1HNF4ADHFRGSTA1
SCHEMBL9273036 1.00 ACMSD (1.00) ACMSDMCL1HNF4ADHFRGSTA1
SCHEMBL9652822 0.98 ACMSD (0.96) ACMSDMCL1HNF4ADHFRGSTA1
SCHEMBL18224311 0.94 ACMSD (0.88) ACMSDMCL1HNF4ADHFRGSTA1
SCHEMBL29374831 0.94 ACMSD (0.88) ACMSDMCL1HNF4ADHFRGSTA1
SCHEMBL29904854 0.91 ACMSD (0.83) ACMSDMCL1HNF4ADHFRLCK
SCHEMBL2771723 0.91 ACMSD (0.83) ACMSDMCL1HNF4ADHFRLCK
SCHEMBL22206257 0.89 ACMSD (0.80) ACMSDMCL1HNF4ADHFRLCK
Methane SCHEMBL28165586 0.89 ACMSD (0.80) ACMSDMCL1HNF4ADHFRLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220362265-A1 THERAPY VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2022-11-17 US claimed
US-12629382-B2 Therapy VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2026-05-19 US disclosed
US-20220362265-A1 THERAPY VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2022-11-17 US disclosed
EP-4021504-A1 THERAPY Vestlandets Innovasjonsselskap AS (NO) 2022-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629382-B2 Therapy NR3C1, MGMT, GRM3 ACMSD 4839/4885MCL1 127/4885HNF4A 1192/4885
US-20220362265-A1 THERAPY GRM3, GLRX3, CBR3 ACMSD 4783/4885MCL1 1383/4885HNF4A 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.