Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.64 |
| ▸ | AHR | P35869 | 3/20 | 0.64 |
| ▸ | ABL1 | P00519 | 2/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | BCR | P11274 | 2/20 | 0.59 |
| ▸ | NQO2 | P16083 | 4/20 | 0.59 |
| ▸ | TTR | P02766 | 2/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | MYC | P01106 | 1/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.58 |
| ▸ | TUBB | P07437 | 5/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976085 | 1.00 | ESR1 (0.64) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL2976010 | 1.00 | ESR1 (0.64) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL1284984 | 0.90 | NQO2 (0.72) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL14027997 | 0.90 | NQO2 (0.72) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL1284983 | 0.90 | NQO2 (0.72) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL2973745 | 0.85 | TUBB1 (0.55) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL2980124 | 0.85 | NQO2 (0.55) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL2981370 | 0.85 | NQO2 (0.55) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL2973741 | 0.85 | TUBB1 (0.55) | ESR1AHRABL1ABCB1BCR | |
| SCHEMBL2980122 | 0.85 | NQO2 (0.55) | ESR1AHRABL1ABCB1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781580-B2 | Stilbene derivatives as new cancer therapeutic agents | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2010-08-24 | — | — | US | disclosed |
| WO-2008131320-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | HDGF, TIE1, VEGFA | ESR1 3637/4885AHR 4030/4885ABL1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.