Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | CASP3 | P42574 | 2/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.63 |
| ▸ | COMT | P21964 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807194 | 0.85 | PARP1 (0.62) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL29761118 | 0.85 | PARP1 (0.62) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL29761123 | 0.84 | NPC1 (0.62) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL28624165 | 0.84 | ALDH1A1 (0.58) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL11973405 | 0.84 | COMT (0.59) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL28050846 | 0.83 | PARP1 (0.72) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL4680814 | 0.80 | HPGD (0.55) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL29761125 | 0.80 | KDR (0.63) | RAB9ANPC1PARP1ALDH1A1TDP1 | |
| SCHEMBL27285123 | 0.79 | PARP1 (0.58) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL29761130 | 0.79 | HDAC8 (0.57) | RAB9ANPC1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214149-B | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2022-08-02 | — | — | CN | disclosed |