Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | COMT | P21964 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27285123 | 0.88 | PARP1 (0.58) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL11807194 | 0.87 | PARP1 (0.62) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL29761118 | 0.87 | PARP1 (0.62) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL111826 | 0.86 | PARP1 (0.70) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL29749881 | 0.86 | PARP1 (0.70) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL16859274 | 0.84 | PARP1 (0.68) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| Hydrochloric Acid SCHEMBL7320778 | 0.84 | PARP1 (0.68) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL4507521 | 0.84 | PARP1 (0.68) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL460456 | 0.84 | PARP1 (1.00) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL31120780 | 0.84 | PARP1 (0.68) | PARP1ALDH1A1LMNAALOX12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214149-B | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-113214149-B | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-113214149-B | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-113214149-A | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214149-A | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214149-A | Synthesis method of phenyl (quinoline-8-yl) ketone derivative | 江苏师范大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-105209468-B | Substitution 7 Azabicyclic compounds and they as orexin receptor conditioning agent purposes | 詹森药业有限公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-105209468-A | Substituted 7-azabicycles and their use as orexin receptor modulators | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |