Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 6/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.87 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.87 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.87 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.77 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29761950 | 0.91 | SLC1A3 (0.84) | SLC1A3HRH3MAPK1HRH4SLC1A2 | |
| SCHEMBL29761962 | 0.87 | SLC1A3 (1.00) | SLC1A3HRH3MAPK1HRH4SLC1A2 | |
| SCHEMBL4024863 | 0.86 | HRH3 (1.00) | SLC1A3HRH3MAPK1HRH4SLC1A2 | |
| SCHEMBL29761980 | 0.84 | SLC1A2 (1.00) | SLC1A3HRH3MAPK1HRH4SLC1A2 | |
| SCHEMBL4020529 | 0.84 | HRH3 (0.79) | SLC1A3HRH3MAPK1HRH4SLC1A2 | |
| SCHEMBL29761967 | 0.84 | SLC1A2 (0.83) | SLC1A3HRH3MAPK1HRH4SLC1A2 | |
| SCHEMBL29761978 | 0.84 | HRH3 (0.74) | SLC1A3HRH3MAPK1HRH4SLC1A2 | |
| SCHEMBL29761958 | 0.84 | HRH3 (0.74) | SLC1A3HRH3MAPK1HRH4SLC1A2 | |
| SCHEMBL4020046 | 0.81 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL22899006 | 0.81 | SLC1A2 (0.82) | SLC1A3HRH3MAPK1HRH4SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267308-A1 | Modulators of Excitatory Amino Acid Transporters and Methods Using Same | DREXEL UNIVERSITY | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267308-A1 | Modulators of Excitatory Amino Acid Transporters and Methods Using Same | SLC1A2, SLC1A1, SLC1A3 | SLC1A3 3/4885HRH3 3145/4885MAPK1 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.