SCHEMBL29761998

SCHEMBL29761998

O=[N+]([O-])c1ccc(O)c(S(=O)(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 2/20 0.59
ALDH1A1 P00352 4/20 0.56
TSHR P16473 3/20 0.56
GPR35 Q9HC97 2/20 0.56
TP53 P04637 1/20 0.56
HPGD P15428 1/20 0.56
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
GAA P10253 1/20 0.55
THRB P10828 1/20 0.55
ERN1 O75460 1/20 0.51
CYP2C19 P33261 1/20 0.47
ALOX15 P16050 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PDE2A O00408 1/20 0.46
PDE5A O76074 1/20 0.46
CYP3A4 P08684 1/20 0.46
NFKB1 P19838 1/20 0.46
APEX1 P27695 1/20 0.46
PDE4A P27815 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5446804 1.00 NT5E (0.59) NT5EALDH1A1TSHRGPR35TP53
SCHEMBL6398137 0.98 NT5E (0.57) NT5EALDH1A1TSHRGPR35TP53
SCHEMBL18301990 0.85 GAA (0.59) NT5EALDH1A1TSHRGPR35TP53
SCHEMBL3182919 0.85 NT5E (0.59) NT5EALDH1A1TSHRGPR35TP53
SCHEMBL6395832 0.84 ALDH1A1 (0.55) NT5EALDH1A1TSHRGPR35TP53
SCHEMBL1530423 0.84 ALDH1A1 (0.55) NT5EALDH1A1TSHRGPR35TP53
SCHEMBL11667865 0.83 PTPRC (0.55) NT5EALDH1A1TSHRGPR35TP53
SCHEMBL10423509 0.82 NT5E (0.68) NT5EALDH1A1TSHRGPR35TP53
SCHEMBL67062 0.81 NT5E (0.59) NT5EALDH1A1TSHRGPR35GAA
SCHEMBL315765 0.81 NT5E (0.59) NT5EALDH1A1TSHRGPR35GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022145110-A1 CORE-SHEATH COMPOSITE FIBER FOR ARTIFICIAL HAIR, HEADWEAR PRODUCT INCLUDING SAME, AND PRODUCTION METHOD FOR SAME 株式会社カネカ 2022-07-07 WO disclosed