SCHEMBL29763100

SCHEMBL29763100

Nc1ncnc2c1ncn2[C@H]1CC[C@@H](COP(O)(=S)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.55
▸ P2RX1 P51575 4/20 0.54
▸ P2RX3 P56373 4/20 0.54
▸ P2RX2 Q9UBL9 2/20 0.54
▸ ENPP1 P22413 3/20 0.53
▸ P2RY11 Q96G91 2/20 0.53
▸ P2RY2 P41231 4/20 0.51
▸ P2RY1 P47900 5/20 0.51
▸ P2RX4 Q99571 3/20 0.51
▸ SRC P12931 2/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ ALDH1A1 P00352 1/20 0.51
▸ DNPH1 O43598 1/20 0.50
▸ PRKAB2 O43741 1/20 0.50
▸ TRPM2 O94759 1/20 0.50
▸ LDHA P00338 1/20 0.50
▸ ADRB2 P07550 1/20 0.50
▸ FBP1 P09467 1/20 0.50
▸ ADORA1 P30542 1/20 0.50
▸ PRKAG1 P54619 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1763090 1.00 POLB (0.55) POLBP2RX1P2RX3P2RX2ENPP1
SCHEMBL4969963 0.93 P2RX3 (0.61) POLBP2RX1P2RX3P2RX2P2RY2
SCHEMBL23978230 0.93 P2RX3 (0.61) POLBP2RX1P2RX3P2RX2P2RY2
SCHEMBL31229395 0.93 P2RX3 (0.61) POLBP2RX1P2RX3P2RX2P2RY2
SCHEMBL19389373 0.92 ENPP1 (0.51) POLBP2RX1P2RX3P2RX2ENPP1
Dda-Triphosphate SCHEMBL79815 0.92 P2RX3 (0.63) POLBP2RX1P2RX3P2RX2P2RY2
SCHEMBL8630966 0.92 P2RX3 (0.63) POLBP2RX1P2RX3P2RX2P2RY2
Dda-Triphosphate SCHEMBL24767736 0.92 P2RX3 (0.63) POLBP2RX1P2RX3P2RX2P2RY2
Dda-Triphosphate SCHEMBL23978346 0.92 P2RX3 (0.63) POLBP2RX1P2RX3P2RX2P2RY2
Dda-Triphosphate SCHEMBL12932305 0.92 P2RX3 (0.63) POLBP2RX1P2RX3P2RX2P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250622-A1 SIMULTANEOUS IMAGING OF NUCLEIC ACID AND PROTEIN IN A SAMPLE GENENTECH, INC. (US) 2025-08-07 — — US disclosed
CN-120202303-A Simultaneous imaging of nucleic acids and proteins in a sample 基因泰克公司 2025-06-24 — — CN disclosed
CN-119789852-A Compositions and methods for delivering RNA 再生技术有限责任公司 2025-04-08 — — CN disclosed
CN-119040472-A Single cell genome abnormality detection method and kit 上海市第一人民医院 2024-11-29 — — CN disclosed
CN-117396193-A Compositions and methods for delivering RNA 再生技术有限责任公司 2024-01-12 — — CN disclosed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 — — EP disclosed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 — — CN disclosed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 — — WO disclosed
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