Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.54 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.53 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.50 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29763100 | 1.00 | POLB (0.55) | POLBP2RX1P2RX3P2RX2ENPP1 | |
| SCHEMBL4969963 | 0.93 | P2RX3 (0.61) | POLBP2RX1P2RX3P2RX2P2RY2 | |
| SCHEMBL23978230 | 0.93 | P2RX3 (0.61) | POLBP2RX1P2RX3P2RX2P2RY2 | |
| SCHEMBL31229395 | 0.93 | P2RX3 (0.61) | POLBP2RX1P2RX3P2RX2P2RY2 | |
| SCHEMBL19389373 | 0.92 | ENPP1 (0.51) | POLBP2RX1P2RX3P2RX2ENPP1 | |
| Dda-Triphosphate SCHEMBL79815 | 0.92 | P2RX3 (0.63) | POLBP2RX1P2RX3P2RX2P2RY2 | |
| SCHEMBL8630966 | 0.92 | P2RX3 (0.63) | POLBP2RX1P2RX3P2RX2P2RY2 | |
| Dda-Triphosphate SCHEMBL24767736 | 0.92 | P2RX3 (0.63) | POLBP2RX1P2RX3P2RX2P2RY2 | |
| Dda-Triphosphate SCHEMBL23978346 | 0.92 | P2RX3 (0.63) | POLBP2RX1P2RX3P2RX2P2RY2 | |
| Dda-Triphosphate SCHEMBL12932305 | 0.92 | P2RX3 (0.63) | POLBP2RX1P2RX3P2RX2P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180355406-A1 | POLYNUCLEIC ACID MOLECULE ENRICHMENT METHODOLOGIES | GENETICS RESEARCH, LLC, D/B/A ZS GENETICS, INC. | 2018-12-13 | — | — | US | claimed |
| US-20240384261-A1 | METHODS, COMPOSITIONS, AND KITS FOR PREPARING SEQUENCING LIBRARY | GENEFIRST LIMITED (GB) | 2024-11-21 | — | — | US | disclosed |
| EP-4312942-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | Rejuvenation Technologies Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| EP-4271389-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | Rejuvenation Technologies Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| US-20220347112-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | REJUVENATION TECHNOLOGIES, INC. | 2022-11-03 | — | — | US | disclosed |
| WO-2022212576-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | REJUVENATION TECHNOLOGIES INC. (US) | 2022-10-06 | — | — | WO | disclosed |
| WO-2022147039-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | REJUVENATION TECHNOLOGIES INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| WO-2022072731-A1 | RAPID AND HIGHLY SENSITIVE LUMINESCENT BIOMOLECULE DETECTION | ASCELLA BIOSYSTEMS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |
| US-20180355406-A1 | POLYNUCLEIC ACID MOLECULE ENRICHMENT METHODOLOGIES | GENETICS RESEARCH, LLC, D/B/A ZS GENETICS, INC. | 2018-12-13 | — | — | US | disclosed |
| US-20180223332-A1 | Nucleic Acid Sample Preparation | CAMBRIDGE EPIGENETIX LIMITED (GB) | 2018-08-09 | — | — | US | disclosed |
| US-20170037465-A1 | Methods for Nucleic Acid Base Determination | TSAVACHIDOU DIMITRA (US) | 2017-02-09 | — | — | US | disclosed |
| US-8614312-B2 | Method for preparing nucleotides and related analogues by synthesis on soluble substrate, and biological tools thus prepared | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-24 | — | — | US | disclosed |
| US-20110118454-A1 | METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-05-19 | — | — | US | disclosed |
| EP-2265624-A1 | METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED | Centre National de la Recherche Scientifique (FR) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009115694-A1 | METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118454-A1 | METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED | PNP, NUDT1, DUT | POLB 209/4885P2RX1 447/4885P2RX3 539/4885 |
| US-20220347112-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF RNA | TERT, PLTP, PCTP | POLB 340/4885P2RX1 4757/4885P2RX3 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.