Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16775785 | 0.84 | ALDH1A1 (0.40) | GRIK1KIF11ALDH1A1SLC1A1 | |
| SCHEMBL16775768 | 0.84 | ALDH1A1 (0.40) | GRIK1KIF11ALDH1A1SLC1A1 | |
| SCHEMBL8520 | 0.84 | ALDH1A1 (0.40) | GRIK1KIF11ALDH1A1SLC1A1 | |
| Hydrochloric Acid SCHEMBL3394169 | 0.82 | ALDH1A1 (0.41) | GRIK1KIF11ALDH1A1SLC1A1 | |
| SCHEMBL29987645 | 0.82 | ALDH1A1 (0.42) | MMEALDH1A1FOLH1TGFBR1 | |
| SCHEMBL934011 | 0.82 | ALDH1A1 (0.42) | MMEALDH1A1FOLH1TGFBR1 | |
| SCHEMBL12580526 | 0.82 | ALDH1A1 (0.42) | MMEALDH1A1FOLH1TGFBR1 | |
| SCHEMBL19359995 | 0.82 | ALDH1A1 (0.42) | MMEALDH1A1FOLH1TGFBR1 | |
| Hydrochloric Acid SCHEMBL3908348 | 0.80 | ALDH1A1 (0.40) | MMEALDH1A1FOLH1TGFBR1 | |
| SCHEMBL10000227 | 0.78 | ALDH1A1 (0.39) | MMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116406355-B | P38 alpha mitogen-activated protein kinase inhibitors | GEN1E生命科学公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-115697980-B | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119384420-A | Novel PAR-2 inhibitors | 多曼治疗学公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-112996814-B | Pharmaceutical combination of anti-CEACAM 6 and anti-PD-1 or anti-PD-L1 antibodies for the treatment of cancer | 拜耳公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-114728949-B | Heterocyclic compounds as kinase inhibitors and uses thereof | 曙方医药 | 2024-11-12 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-115210238-B | Substituted aminoquinolones as dgkα inhibitors for immune activation | 拜耳公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-113164778-B | Pharmaceutical combinations of anti-CEACAM 6 and TIM3 antibodies | 拜耳公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-118184628-A | Crystalline forms of a compound | 拜耳医药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118201638-A | Biosoluble polymers or particles for delivery of active agents and methods of manufacture | 蒂贾尼控股有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-111727183-B | Use of 5-fluoro-4- (4-fluoro-2-methoxyphenyl) -N- {4- [ (S-methylsulfonyl) methyl ] pyridin-2-yl } pyridin-2-amine for the treatment of diffuse large B cell lymphomas | 拜耳公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-115812151-A | Methods, arrays and uses thereof | 免疫媒介有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-115151533-A | MEK inhibitors and therapeutic uses thereof | 医疗免疫工程公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114933585-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-08-23 | — | — | CN | disclosed |
| CN-108912066-B | Therapeutically active compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2022-06-24 | — | — | CN | disclosed |