SCHEMBL8520

SCHEMBL8520

COC(=O)C(N)CC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
KIF11 P52732 1/20 0.36
GRIK1 P39086 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC1A1 P43005 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16775785 1.00 ALDH1A1 (0.40) ALDH1A1TDP1MGAMGAASI
SCHEMBL16775768 1.00 ALDH1A1 (0.40) ALDH1A1TDP1MGAMGAASI
Hydrochloric Acid SCHEMBL3394169 0.98 ALDH1A1 (0.41) ALDH1A1TDP1MGAMGAASI
SCHEMBL29763322 0.84 MME (0.34) ALDH1A1KIF11GRIK1SLC1A1
SCHEMBL8894673 0.82 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2KIF11CA1CA2
SCHEMBL25006833 0.82 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2KIF11GRIK1CA1
SCHEMBL10458343 0.82 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2KIF11GRIK1CA1
SCHEMBL30765423 0.81 GRIK1 (0.32) ALDH1A1MGAMGAASIMGAM2
Methyl Aminolevulinate SCHEMBL15345257 0.81 LMNA (0.61) ALDH1A1MGAMGAASIMGAM2
SCHEMBL6259101 0.81 KMT2A (0.37) SMN1; SMN2KIF11KMT2ASLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3657 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719373-A1 PHOTODYNAMIC THERAPY COMBINATIONS FOR IMPROVEMENT OF ACTINIC KERATOSIS, ACNE AND BASAL CELL CARCINOMA Alexandroff, Anton (GB) 2026-04-08 EP claimed
US-20260085061-A1 PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS SITRYX THERAPEUTICS LIMITED (GB) 2026-03-26 US claimed
US-12433477-B2 Contrast enhancement for medical imaging STRYKER CORPORATION (US) 2025-10-07 US claimed
EP-4612132-A1 PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS Sitryx Therapeutics Limited (GB) 2025-09-10 EP claimed
US-12364682-B2 Use of tegaserod in preparation of anti-tumor drug QINGDAO HAIJI BIOMEDICINE CO., LTD. (CN) 2025-07-22 US claimed
CN-120166987-A Phthalazine derivatives as pyruvate kinase modulators 西特瑞治疗有限公司 2025-06-17 CN claimed
WO-2025121735-A1 PHARMACEUTICAL COMPOSITION COMPRISING UPCONVERSION NANOPARTICLES FOR PREVENTING OR TREATING CANCER 부산대학교 산학협력단 2025-06-12 WO claimed
US-20250177423-A1 PHOTORESPONSIVE PEPTIDE DELIVERY SYSTEM AND METHOD OF USING THE SAME THE UNIVERSITY OF HONG KONG (CN) 2025-06-05 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-12280050-B2 Therapeutic compositions, combinations, and methods of use THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2025-04-22 US claimed
US-20080125485-A1 2-(acetyloxy)-5-hydroxybenzenesulfonic acid, or 5-(acetyloxy)-2-hydroxybenzene-sulfonic acid, or 2,5-bis(acetyloxy)benzenesulfonic acid; skin disorders like skin wrinkles, actinic keratosis, skin pigmentation and hyperpigmentation, hirsutism and hypertricosis, obesity due to adipogenesis ACTION MEDICINES (ES) 2008-05-29 US claimed
US-20080114060-A1 2-(acetyloxy)-5-hydroxybenzenesulfonic acid, or 5-(acetyloxy)-2-hydroxybenzene-sulfonic acid, or 2,5-bis(acetyloxy)benzenesulfonic acid, or sultosilic acid for example; combination therapy with other drugs or photodynamic therapy ACTION MEDICINES (ES) 2008-05-15 US claimed
WO-2008048190-A1 UPCONVERSION FLUORESCENT NANO-STRUCTURED MATERIAL AND USES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2008-04-24 WO claimed
WO-2008020027-A2 2,5-DIHYDROXYBENZENE COMPOUNDS FOR THE TREATMENT OF SKIN CANCER ACTION MEDICINES, S.L. (ES) 2008-02-21 WO claimed
WO-2008020025-A1 USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR TREATING ACTINIC KERATOSIS ACTION MEDICINES, S.L. (ES) 2008-02-21 WO claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2004024144-A9 METHOD OF TREATING SKIN DISORDERS CANDELA CORP (US) 2004-06-17 WO claimed
WO-2004024144-A1 METHOD OF TREATING SKIN DISORDERS CANDELA CORPORATION (US) 2004-03-25 WO claimed
US-20040048842-A1 Method of treating skin disorders CANDELA CORPORATION 2004-03-11 US claimed