Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 5/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.64 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795068 | 1.00 | HDAC2 (0.64) | HDAC2HDAC3HDAC8NCOR1HTT | |
| SCHEMBL28329638 | 0.82 | HTT (0.74) | HDAC2HDAC3HDAC8HTTHDAC6 | |
| SCHEMBL11252751 | 0.82 | HTT (0.78) | HDAC2HDAC3HDAC8HTTHDAC6 | |
| SCHEMBL28871403 | 0.78 | HDAC2 (1.00) | HDAC2HDAC3HDAC8NCOR1HDAC6 | |
| SCHEMBL9464308 | 0.78 | HTT (0.89) | HDAC2HDAC3HDAC8HTTHDAC6 | |
| SCHEMBL9464627 | 0.76 | POLB (0.88) | HDAC2HDAC3HDAC8HTTHDAC6 | |
| SCHEMBL29894470 | 0.75 | POLB (0.73) | HDAC2HDAC3HDAC8HTTHDAC6 | |
| SCHEMBL21565076 | 0.75 | POLB (0.73) | HDAC2HDAC3HDAC8HTTHDAC6 | |
| SCHEMBL29763592 | 0.75 | POLB (0.47) | HDAC2HDAC3HDAC6HDAC1POLB | |
| SCHEMBL28561573 | 0.74 | POLB (0.64) | HDAC2HDAC3HDAC8HTTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | disclosed |