Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MECP2 | P51608 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205773 | 0.83 | KCNQ2 (0.59) | POLBTDP1MAPTTP53KMT2A | |
| SCHEMBL29763593 | 0.75 | HDAC2 (0.64) | POLBTDP1MAPTKMT2AMEN1 | |
| SCHEMBL28795068 | 0.75 | HDAC2 (0.64) | POLBTDP1MAPTKMT2AMEN1 | |
| SCHEMBL2117010 | 0.73 | EGFR (0.49) | TDP1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28252022 | 0.72 | NLN (0.64) | POLBTDP1MAPTTP53KMT2A | |
| SCHEMBL28252023 | 0.72 | NLN (0.64) | POLBTDP1MAPTTP53KMT2A | |
| SCHEMBL29362308 | 0.70 | ALDH1A1 (0.52) | TDP1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2967462 | 0.70 | ALDH1A1 (0.52) | TDP1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29152858 | 0.70 | SLC40A1 (0.70) | POLBTDP1MAPTTP53KMT2A | |
| SCHEMBL7473362 | 0.70 | EGFR (0.50) | TDP1MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | disclosed |