SCHEMBL297639

SCHEMBL297639

CC1CC(C)(C)CC(c2ccc(O)c(-c3ccccc3)c2)(c2ccc(O)c(-c3ccccc3)c2)C1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.57
ESR2 Q92731 2/20 0.57
BACE1 P56817 2/20 0.39
ALDH1A1 P00352 4/20 0.37
CCR2 P41597 3/20 0.36
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PELI1 Q96FA3 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
CYP2D6 P10635 2/20 0.34
CYP3A4 P08684 2/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALOX12 P18054 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30060373 1.00 ESR1 (0.57) ESR1ESR2BACE1ALDH1A1CCR2
SCHEMBL7653011 0.91 ESR1 (0.48) ESR1ESR2BACE1ALDH1A1CCR2
SCHEMBL4760757 0.91 ESR2 (0.48) ESR1ESR2BACE1ALDH1A1CCR2
SCHEMBL298691 0.86 ESR2 (0.56) ESR1ESR2BACE1ALDH1A1CCR2
SCHEMBL21538491 0.82 ESR1 (0.69) ESR1ESR2ALDH1A1CYP2D6CYP3A4
SCHEMBL296665 0.81 ESR1 (0.50) ESR1ESR2BACE1ALDH1A1CCR2
SCHEMBL297426 0.81 ESR1 (0.50) ESR1ESR2BACE1ALDH1A1CCR2
SCHEMBL29404012 0.79 ESR1 (0.65) ESR1ESR2ALDH1A1CCR2CYP3A4
SCHEMBL244496 0.79 ESR1 (0.65) ESR1ESR2ALDH1A1CCR2CYP3A4
SCHEMBL29459501 0.79 ESR1 (0.65) ESR1ESR2ALDH1A1CCR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-20250179244-A1 POLYCARBONATE RESIN AND MOLDED PRODUCT CONTAINING SAME FUJIFILM CORPORATION (JP) 2025-06-05 US disclosed
US-20250122374-A1 FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION AND MOLDED PRODUCT THEREOF TEIJIN LIMITED (JP) 2025-04-17 US disclosed
US-20250034327-A1 POLYESTER RESIN AND MOLDED PRODUCT INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2025-01-30 US disclosed
EP-4471089-A1 FLAME RETARDANT POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Teijin Limited (JP) 2024-12-04 EP disclosed
WO-2024071045-A1 POLYCARBONATE RESIN AND MOLDED ARTICLE CONTAINING SAME 富士フイルム株式会社 2024-04-04 WO disclosed
US-20240101859-A1 RESIN COMPOSITION FOR COATING, POLYMER, METHOD FOR PRODUCING POLYMER, COATING FILM, AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2024-03-28 US disclosed
US-20240092967-A1 RESIN COMPOSITION FOR COATING, POLYMER, METHOD FOR PRODUCING POLYMER, COATING FILM, AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2024-03-21 US disclosed
EP-0419926-B1 Thermoplastic alloys with polyesters and polyestercarbonates based on substituted cycloalkylidenebisphenols BAYER AG (DE) 1997-12-10 EP disclosed
EP-0443058-B1 Polyesters and polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes BAYER AG (DE) 1997-04-23 EP disclosed
US-5512632-A MOLDING MATERIAL BAYER AKTIENGESELLSCHAFT (DE) 1996-04-30 US disclosed
EP-0691201-A2 Spray-coated laminats with colour layer BAYER AG (DE) 1996-01-10 EP disclosed
EP-0443058-A1 Polyesters and polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes BAYER AG (DE) 1991-08-28 EP disclosed
US-5041521-A High impact strength, stress releiving, noncracking BAYER AKTIENGESELLSCHAFT (DE) 1991-08-20 US disclosed
EP-0419926-A1 Thermoplastic alloys with polyesters and polyestercarbonates based on substituted cycloalkylidenebisphenols BAYER AG (DE) 1991-04-03 EP disclosed