SCHEMBL298691

SCHEMBL298691

CC1CC(C)(C)CC(c2cc(-c3ccccc3)c(O)c(-c3ccccc3)c2)(c2cc(-c3ccccc3)c(O)c(-c3ccccc3)c2)C1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.56
ESR1 P03372 1/20 0.56
CCR2 P41597 4/20 0.37
BACE1 P56817 2/20 0.36
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 2/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALOX12 P18054 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
PDE4B Q07343 1/20 0.33
PTPN1 P18031 1/20 0.32
AVPR2 P30518 1/20 0.31
AVPR1A P37288 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296665 0.91 ESR1 (0.50) ESR2ESR1CCR2BACE1ALDH1A1
SCHEMBL297426 0.91 ESR1 (0.50) ESR2ESR1CCR2BACE1ALDH1A1
SCHEMBL297639 0.86 ESR1 (0.57) ESR2ESR1CCR2BACE1ALDH1A1
SCHEMBL30060373 0.86 ESR1 (0.57) ESR2ESR1CCR2BACE1ALDH1A1
SCHEMBL4760757 0.84 ESR2 (0.48) ESR2ESR1CCR2BACE1ALDH1A1
SCHEMBL5670562 0.80 ESR1 (0.48) ESR2ESR1CCR2ALDH1A1CYP3A4
SCHEMBL7653011 0.79 ESR1 (0.48) ESR2ESR1CCR2BACE1ALDH1A1
SCHEMBL827205 0.78 ESR1 (0.69) ESR2ESR1CCR2ALDH1A1CYP3A4
SCHEMBL9472412 0.77 ESR1 (0.67) ESR2ESR1CCR2ALDH1A1CYP3A4
SCHEMBL21624439 0.77 ESR1 (0.88) ESR2ESR1CCR2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1560871-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2004041907-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-05-21 WO claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
US-20250122374-A1 FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION AND MOLDED PRODUCT THEREOF TEIJIN LIMITED (JP) 2025-04-17 US disclosed
EP-4471089-A1 FLAME RETARDANT POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Teijin Limited (JP) 2024-12-04 EP disclosed
US-20240101859-A1 RESIN COMPOSITION FOR COATING, POLYMER, METHOD FOR PRODUCING POLYMER, COATING FILM, AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2024-03-28 US disclosed
US-20240092967-A1 RESIN COMPOSITION FOR COATING, POLYMER, METHOD FOR PRODUCING POLYMER, COATING FILM, AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2024-03-21 US disclosed
EP-4339251-A1 COATING RESIN COMPOSITION, POLYMER, POLYMER PRODUCTION METHOD, COATING FILM AND PRODUCTION METHOD THEREFOR FUJIFILM Corporation (JP) 2024-03-20 EP disclosed
EP-0443058-B1 Polyesters and polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes BAYER AG (DE) 1997-04-23 EP disclosed
US-5512632-A MOLDING MATERIAL BAYER AKTIENGESELLSCHAFT (DE) 1996-04-30 US disclosed
EP-0691201-A2 Spray-coated laminats with colour layer BAYER AG (DE) 1996-01-10 EP disclosed
EP-0443058-A1 Polyesters and polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes BAYER AG (DE) 1991-08-28 EP disclosed
US-5041521-A High impact strength, stress releiving, noncracking BAYER AKTIENGESELLSCHAFT (DE) 1991-08-20 US disclosed
EP-0419926-A1 Thermoplastic alloys with polyesters and polyestercarbonates based on substituted cycloalkylidenebisphenols BAYER AG (DE) 1991-04-03 EP disclosed