Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | TDO2 | P48775 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928664 | 0.84 | GFER (0.69) | GFERGLAPKMALDH1A1MAPT | |
| SCHEMBL3915047 | 0.84 | GLA (0.78) | GFERGLAPKMTDO2RAB9A | |
| SCHEMBL2989085 | 0.83 | GFER (0.64) | GFERGLAPKMTDO2RAB9A | |
| SCHEMBL23884729 | 0.81 | GFER (0.62) | GFERGLAPKMTDO2RAB9A | |
| SCHEMBL15372156 | 0.80 | GFER (0.64) | GFERGLAPKMTDO2RAB9A | |
| SCHEMBL29764424 | 0.80 | MAPT (0.69) | GLAPKMTDO2ALDH1A1MAPT | |
| SCHEMBL1487124 | 0.79 | PKM (0.50) | GFERGLAPKMTDO2RAB9A | |
| SCHEMBL3225812 | 0.77 | PKM (0.66) | GFERGLAPKMTDO2RAB9A | |
| SCHEMBL3217362 | 0.76 | PKM (0.69) | GFERPKMLMNA | |
| SCHEMBL17396 | 0.75 | POLB (0.61) | GFERGLAPKMTDO2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |