Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834639 | 0.88 | GLA (1.00) | GLAGFERMMP2TDO2LMNA | |
| SCHEMBL3928664 | 0.84 | GFER (0.69) | GLAGFERMMP2PKMLMNA | |
| SCHEMBL29764438 | 0.84 | GFER (0.65) | GLAGFERPKMTDO2RAB9A | |
| SCHEMBL2989085 | 0.83 | GFER (0.64) | GLAGFERMMP2PKMTDO2 | |
| SCHEMBL23884729 | 0.81 | GFER (0.62) | GLAGFERPKMTDO2RAB9A | |
| SCHEMBL15372156 | 0.80 | GFER (0.64) | GLAGFERPKMTDO2RAB9A | |
| SCHEMBL18498622 | 0.80 | GLA (0.58) | GLAMMP2LMNATSHRHTT | |
| SCHEMBL3824011 | 0.80 | MAPT (0.69) | GLAMMP2PKMLMNATSHR | |
| Hydrochloric Acid SCHEMBL19857662 | 0.78 | MAPT (0.67) | GLAMMP2PKMLMNATSHR | |
| SCHEMBL3225812 | 0.77 | PKM (0.66) | GLAGFERPKMTDO2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035372-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008005338-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2008-01-10 | — | — | WO | disclosed |
| WO-2007039580-A1 | IMIDAZOLYL-SUBSTITUTED BENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039578-A1 | IMIDAZOLYL-SUBSTITUTED AZABENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |