Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17980040 | 1.00 | GPR119 (0.37) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL17980038 | 1.00 | GPR119 (0.37) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL24080187 | 1.00 | GPR119 (0.37) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL25400278 | 1.00 | GPR119 (0.37) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL17980020 | 0.91 | GPR119 (0.40) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL21081109 | 0.91 | GPR119 (0.40) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL17980017 | 0.91 | GPR119 (0.40) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL17980088 | 0.88 | ALDH1A1 (0.36) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL17980086 | 0.88 | ALDH1A1 (0.36) | GPR119ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL30029680 | 0.88 | ALDH1A1 (0.36) | GPR119ALDH1A1TSHRLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4046995-B1 | 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-4046995-A1 | 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS | Sunovion Pharmaceuticals Inc. (US) | 2022-08-24 | — | — | EP | disclosed |