Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3949410 | 0.97 | TSHR (0.33) | ALDH1A1TDP1TSHRCYP3A4 | |
| Water SCHEMBL16146551 | 0.89 | — | — | |
| SCHEMBL304 | 0.89 | — | — | |
| SCHEMBL27707921 | 0.86 | — | — | |
| Iodide SCHEMBL28254110 | 0.86 | — | — | |
| Methane SCHEMBL21533321 | 0.86 | — | — | |
| Acetonitrile SCHEMBL3841070 | 0.83 | — | — | |
| SCHEMBL27854025 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TDP1TSHR | |
| Ethylene Glycol SCHEMBL28280704 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TDP1TSHR | |
| Bicarbonate SCHEMBL11484851 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114394-B1 | PLATINUM ANALOGS WITH BIS-NITRILE-CONTAINING LIGANDS | BIONUMERIK PHARMACEUTICALS INC (US) | 2012-08-15 | — | — | EP | claimed |
| US-7777060-B2 | Platinum analogs with bis-nitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | claimed |
| EP-2114394-B1 | PLATINUM ANALOGS WITH BIS-NITRILE-CONTAINING LIGANDS | BIONUMERIK PHARMACEUTICALS INC (US) | 2012-08-15 | — | — | EP | disclosed |
| US-7777060-B2 | Platinum analogs with bis-nitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| EP-2114394-A1 | PLATINUM ANALOGS WITH BIS-NITRILE-CONTAINING LIGANDS | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008100301-A1 | PLATINUM ANALOGS WITH BIS-NITRILE-CONTAINING LIGANDS | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |
| US-20080194680-A1 | Platinum analogs with bis-nitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194680-A1 | Platinum analogs with bis-nitrile-containing ligands | PCNA, LIG4, TOP2B | ALDH1A1 2084/4885TDP1 1028/4885TSHR 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.