Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.51 |
| ▸ | TLR2 | O60603 | 3/20 | 0.50 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29812585 | 1.00 | KMT2A (0.53) | KMT2AMDM2TLR2TLR1KLK7 | |
| SCHEMBL24246257 | 1.00 | KMT2A (0.53) | KMT2AMDM2TLR2TLR1KLK7 | |
| SCHEMBL16870063 | 1.00 | KMT2A (0.53) | KMT2AMDM2TLR2TLR1KLK7 | |
| SCHEMBL24246233 | 0.98 | KMT2A (0.52) | KMT2AMDM2TLR2TLR1KLK7 | |
| SCHEMBL999302 | 0.92 | KMT2A (0.58) | KMT2AMDM2TLR2TLR1KLK7 | |
| SCHEMBL2292778 | 0.92 | MDM2 (0.59) | KMT2AMDM2TLR2TLR1ALDH1A1 | |
| SCHEMBL1738182 | 0.92 | MDM2 (0.59) | KMT2AMDM2TLR2TLR1ALDH1A1 | |
| SCHEMBL2524769 | 0.92 | MDM2 (0.59) | KMT2AMDM2TLR2TLR1ALDH1A1 | |
| SCHEMBL30886226 | 0.92 | MDM2 (0.59) | KMT2AMDM2TLR2TLR1ALDH1A1 | |
| SCHEMBL12040103 | 0.92 | KMT2A (0.58) | KMT2AMDM2TLR2TLR1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271387-A1 | NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCS CONTAINING AND USE THEREOF | Immunext, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| WO-2023186072-A1 | LIGAND-DRUG CONJUGATE AND USE THEREOF | 江苏先声药业有限公司 | 2023-10-05 | — | — | WO | disclosed |
| EP-4136118-A1 | ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF | Immunext, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2022150637-A1 | NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF | IMMUNEXT, INC. (US) | 2022-07-14 | — | — | WO | disclosed |