SCHEMBL999302

SCHEMBL999302

CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
MDM2 Q00987 6/20 0.57
TLR2 O60603 3/20 0.56
TLR1 Q15399 1/20 0.56
KLK7 P49862 1/20 0.49
KLK5 Q9Y337 1/20 0.49
ALDH1A1 P00352 1/20 0.49
TSHR P16473 1/20 0.49
MDM4 O15151 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
IDO1 P14902 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362262 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL29401707 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL2267346 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL30885878 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL12040103 1.00 KMT2A (0.58) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL1000135 0.99 KMT2A (0.60) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL7392221 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL7815145 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL17669898 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7
SCHEMBL30441695 0.97 MDM2 (0.57) KMT2AMDM2TLR2TLR1KLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 US disclosed
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 US disclosed
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-12-25 US disclosed
US-12383560-B2 Compounds and uses thereof FOGHORN THERAPEUTICS INC. (US) 2025-08-12 US disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
WO-2025134068-A1 ANTIBODY DRUG CONJUGATES TARGETING PROTEINOPATHIES, AND USES THEREOF AC IMMUNE SA (CH) 2025-06-26 WO disclosed
US-20250195683-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEROF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-06-19 US disclosed
WO-2025128626-A1 HYBRID PEPTIDE COMPOUNDS HAVING A MODIFIED LYSINE RESIDUE CARMOT THERAPEUTICS, INC. (US) 2025-06-19 WO disclosed
WO-2025128624-A2 HYBRID PEPTIDE COMPOUNDS HAVING A SUBSTITUTED TRYPTOPHAN RESIDUE OR A TERMINAL SUBSTITUENT CARMOT THERAPEUTICS, INC. (US) 2025-06-19 WO disclosed
US-20070293530-A1 SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS METHYLGENE INC. (CA) 2007-12-20 US disclosed
US-20070021434-A1 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF MIGENIX INC. (CA) 2007-01-25 US disclosed
WO-2007002639-A2 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF MIGENIX INC. (CA) 2007-01-04 WO disclosed
EP-1656390-A2 COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF MIGENIX INC. (CA) 2006-05-17 EP disclosed
US-20050153876-A1 Compositions of lipopeptide antibiotic derivatives and methods of use thereof MIGENIX INC. (CA) 2005-07-14 US disclosed
WO-2005000878-A2 COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF MIGENIX INC. (CA) 2005-01-06 WO disclosed
US-5386011-A Antiinflammatory agents; also, peptidomimetic compounds, i,e., agonists, having immunoregulatory effect against infections and cancer ABBOTT LABORATORIES (US) 1995-01-31 US disclosed
EP-0564588-A4 HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS 1993-12-29 EP disclosed
EP-0564588-A1 HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS. ABBOTT LAB (US) 1993-10-13 EP disclosed
WO-1992011858-A1 HEXA- AND HEPTAPEPTIDE ANAPHYLATOXIN-RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 1992-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195683-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEROF CD47, ABCB1, EGFR KMT2A 2537/4885MDM2 2059/4885TLR2 2732/4885
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 KMT2A 3715/4885MDM2 1169/4885TLR2 4438/4885
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 KMT2A 1606/4885MDM2 2085/4885TLR2 3185/4885
US-20070021434-A1 NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF HAVCR2, ADAR, NSUN2 KMT2A 3406/4885MDM2 3730/4885TLR2 2757/4885
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF BID, BCL2, MCL1 KMT2A 719/4885MDM2 384/4885TLR2 4179/4885
US-12383560-B2 Compounds and uses thereof VHL, CLN6, TFEB KMT2A 792/4885MDM2 2551/4885TLR2 4839/4885
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 KMT2A 2434/4885MDM2 3219/4885TLR2 1153/4885
US-20050153876-A1 Compositions of lipopeptide antibiotic derivatives and methods of use thereof NRDC, NOD2, NGLY1 KMT2A 4429/4885MDM2 2032/4885TLR2 20/4885
US-20070293530-A1 SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS HDAC1, HDAC11, HAT1 KMT2A 37/4885MDM2 2883/4885TLR2 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.