SCHEMBL29768873

SCHEMBL29768873

O=CC(CCC(=O)O)NC(=O)CNC(=O)CBr

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 3/20 0.33
▸ RIMKLA Q8IXN7 1/20 0.33
▸ NAALAD2 Q9Y3Q0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24622228 0.75 HPGDS (0.41) FOLH1RIMKLANAALAD2
SCHEMBL25129090 0.75 FOLH1 (0.40) FOLH1RIMKLANAALAD2
SCHEMBL12324731 0.75 PLA2G2C (0.39) FOLH1RIMKLANAALAD2
SCHEMBL16181956 0.75 CTSC (0.39) FOLH1RIMKLANAALAD2
SCHEMBL29768848 0.75 CTSC (0.39) FOLH1RIMKLANAALAD2
SCHEMBL10060881 0.75 FOLH1 (0.41) FOLH1RIMKLANAALAD2
SCHEMBL173035 0.75 PLA2G2C (0.42) FOLH1RIMKLANAALAD2
SCHEMBL24486692 0.75 PLA2G2C (0.42) FOLH1RIMKLANAALAD2
SCHEMBL22731801 0.75 CTSC (0.39) FOLH1RIMKLANAALAD2
SCHEMBL22731832 0.75 GLO1 (0.39) FOLH1RIMKLANAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4271387-A1 NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCS CONTAINING AND USE THEREOF Immunext, Inc. (US) 2023-11-08 — — EP disclosed
WO-2022150637-A1 NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF IMMUNEXT, INC. (US) 2022-07-14 — — WO disclosed
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