Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 6/20 | 0.54 |
| ▸ | NMT2 | O60551 | 5/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | TFPI | P10646 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740541 | 0.93 | NMT1 (0.50) | NMT1NMT2NOD1TLR2OPRL1 | |
| SCHEMBL10740555 | 0.93 | NMT1 (0.50) | NMT1NMT2NOD1TLR2OPRL1 | |
| SCHEMBL30753565 | 0.92 | NMT1 (0.54) | NMT1NMT2NOD1TLR2SLC6A5 | |
| SCHEMBL30882784 | 0.89 | NMT1 (0.49) | NMT1NMT2TLR2OPRL1TFPI | |
| SCHEMBL10745610 | 0.88 | NMT1 (0.51) | NMT1NMT2TLR2OPRL1GRIN2D | |
| SCHEMBL10745622 | 0.88 | NMT1 (0.51) | NMT1NMT2TLR2OPRL1GRIN2D | |
| SCHEMBL10646369 | 0.88 | NOD1 (0.49) | NMT1NMT2NOD1FOLH1 | |
| SCHEMBL10646360 | 0.88 | NOD1 (0.49) | NMT1NMT2NOD1FOLH1 | |
| SCHEMBL30423734 | 0.87 | NMT1 (0.50) | NMT1NMT2TLR2GRIN2DGRIN3B | |
| SCHEMBL29625795 | 0.87 | NOD1 (0.55) | NMT1NMT2NOD1SLC6A5FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284518-A1 | FIBROBLAST ACTIVATION PROTEIN MODULATION TO ALTER IMMUNE CELL MIGRATION AND TUMOR INFILTRATION | Georgetown University (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022165019-A1 | FIBROBLAST ACTIVATION PROTEIN MODULATION TO ALTER IMMUNE CELL MIGRATION AND TUMOR INFILTRATION | GEORGETOWN UNIVERSITY (US) | 2022-08-04 | — | — | WO | disclosed |