SCHEMBL10646360

SCHEMBL10646360

CC(N)C(=O)NCC(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 2/20 0.49
▸ NMT2 O60551 1/20 0.39
▸ NMT1 P30419 1/20 0.39
▸ GLO1 Q04760 1/20 0.37
▸ OPRM1 P35372 3/20 0.37
▸ OPRD1 P41143 3/20 0.37
▸ BMP1 P13497 1/20 0.37
▸ TASP1 Q9H6P5 1/20 0.36
▸ PTGS1 P23219 1/20 0.36
▸ GSTK1 Q9Y2Q3 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ OPRK1 P41145 1/20 0.36
▸ APC P25054 1/20 0.36
▸ FOLH1 Q04609 1/20 0.36
▸ TERT O14746 1/20 0.36
▸ MME P08473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10646369 1.00 NOD1 (0.49) NOD1NMT2NMT1GLO1OPRM1
SCHEMBL7614745 0.92 NOD1 (0.52) NOD1GLO1BMP1PTGS1GSTK1
SCHEMBL7614754 0.92 NOD1 (0.52) NOD1GLO1BMP1PTGS1GSTK1
SCHEMBL29350589 0.91 NOD1 (0.47) NOD1NMT2NMT1GLO1PTGS1
SCHEMBL258819 0.90 NOD1 (0.42) NOD1NMT2NMT1GLO1OPRM1
SCHEMBL29769744 0.88 NMT1 (0.54) NOD1NMT2NMT1FOLH1
SCHEMBL29353451 0.87 FOLH1 (0.44) NOD1NMT2NMT1OPRM1OPRD1
SCHEMBL30920966 0.85 NOD1 (0.52) NOD1GLO1BMP1PTGS1GSTK1
SCHEMBL30320500 0.84 OPRM1 (0.43) NOD1GLO1OPRM1OPRD1OPRK1
SCHEMBL29351781 0.84 MME (0.47) NOD1GLO1OPRM1OPRD1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865857-B2 Medical device with predefined activated cellular integration SOFRADIM PRODUCTION (FR) 2014-10-21 — — US claimed
US-4732155-A Implantable chemoattractant system THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1988-03-22 — — US claimed
US-8865857-B2 Medical device with predefined activated cellular integration SOFRADIM PRODUCTION (FR) 2014-10-21 — — US disclosed
US-20130143976-A1 MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION SOFRADIM PRODUCTION (FR) 2013-06-06 — — US disclosed
US-4732155-A Implantable chemoattractant system THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1988-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130143976-A1 MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION CCL2, MIF, C3AR1 NOD1 1477/4885NMT2 3928/4885NMT1 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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