Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 5/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26907950 | 1.00 | TDO2 (0.55) | TDO2GRM2TDP1LCKIRAK4 | |
| SCHEMBL3475681 | 0.91 | GRM2 (0.57) | TDO2GRM2TDP1MAPTHCAR3 | |
| SCHEMBL29769995 | 0.80 | GRM2 (0.44) | TDO2GRM2MAPTHCAR3HPGDS | |
| SCHEMBL26907901 | 0.80 | GRM2 (0.44) | TDO2GRM2MAPTHCAR3HPGDS | |
| SCHEMBL10625058 | 0.78 | TDO2 (0.59) | TDO2GRM2MAPT | |
| Hydrochloric Acid SCHEMBL29769997 | 0.78 | SMN1; SMN2 (0.48) | TDP1IRAK4MAPTHCAR3HPGDS | |
| Hydrochloric Acid SCHEMBL26907902 | 0.78 | SMN1; SMN2 (0.48) | TDP1IRAK4MAPTHCAR3HPGDS | |
| SCHEMBL19848202 | 0.76 | MAPT (0.61) | TDP1MAPTHCAR3MGAMAMY1A | |
| SCHEMBL19911513 | 0.75 | HCAR3 (0.47) | TDP1MAPTHCAR3HTR2CMGAM | |
| SCHEMBL19911508 | 0.75 | HCAR3 (0.47) | TDP1MAPTHCAR3MGAMAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116724026-A | Novel benzotriazole derivatives having inhibitory activity against dinucleotide pyrophosphatase-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-09-08 | — | — | CN | claimed |
| WO-2022164249-A1 | NOVEL BENZOTRIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE, AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-08-04 | — | — | WO | claimed |
| CN-116724026-A | Novel benzotriazole derivatives having inhibitory activity against dinucleotide pyrophosphatase-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-09-08 | — | — | CN | disclosed |
| WO-2022164249-A1 | NOVEL BENZOTRIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE, AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-08-04 | — | — | WO | disclosed |