SCHEMBL29770525

SCHEMBL29770525

CC(=O)OC[C@]1(COCc2ccccc2)O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@H](OC(C)=O)[C@@H]1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.47
PRKAB2 O43741 1/20 0.43
PRKAG1 P54619 1/20 0.43
PRKAA2 P54646 1/20 0.43
PRKAA1 Q13131 1/20 0.43
PRKAG3 Q9UGI9 1/20 0.43
PRKAG2 Q9UGJ0 1/20 0.43
PRKAB1 Q9Y478 1/20 0.43
P2RY12 Q9H244 3/20 0.41
ADORA3 P0DMS8 2/20 0.40
ADORA1 P30542 2/20 0.40
ADORA2A P29274 1/20 0.40
ACHE P22303 1/20 0.38
AHCY P23526 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1096076 1.00 PRMT6 (0.47) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL5557366 0.93 PRMT6 (0.48) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL5557369 0.93 PRMT6 (0.48) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL16648583 0.92 PRMT6 (0.47) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL23989259 0.92 PRMT6 (0.45) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL21333923 0.92 PRMT6 (0.46) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL3219117 0.89 PRMT6 (0.47) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL28602758 0.89 PRMT6 (0.47) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL28602756 0.89 PRMT6 (0.47) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL23243930 0.87 ACHE (0.42) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4025582-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-07-13 EP disclosed