Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.97 |
| ▸ | BACE1 | P56817 | 4/20 | 0.97 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.97 |
| ▸ | MAOB | P27338 | 6/20 | 0.71 |
| ▸ | PTGES | O14684 | 1/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | TRPM7 | Q96QT4 | 1/20 | 0.67 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21710543 | 1.00 | APP (0.97) | APPBACE1PTPN1MAOBPTGES | |
| SCHEMBL15363878 | 1.00 | APP (0.97) | APPBACE1PTPN1MAOBPTGES | |
| SCHEMBL15363875 | 1.00 | APP (0.97) | APPBACE1PTPN1MAOBPTGES | |
| Grifolic Acid SCHEMBL12180037 | 0.99 | APP (1.00) | APPBACE1PTPN1MAOBPTGES | |
| Grifolic Acid SCHEMBL20819669 | 0.99 | APP (1.00) | APPBACE1PTPN1MAOBPTGES | |
| SCHEMBL2725955 | 0.91 | APP (0.81) | APPBACE1PTPN1MAOBPTGES | |
| SCHEMBL23523338 | 0.87 | BACE1 (0.76) | APPBACE1PTPN1MAOBPTGES | |
| SCHEMBL23523334 | 0.87 | BACE1 (0.76) | APPBACE1PTPN1MAOBPTGES | |
| SCHEMBL15375169 | 0.86 | APP (0.74) | APPBACE1PTPN1MAOBPTGES | |
| SCHEMBL25560668 | 0.86 | SLC6A3 (0.79) | APPBACE1PTPN1MAOBPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374473-A1 | PRENYLTRANSFERASE VARIANTS AND METHODS FOR PRODUCTION OF PRENYLATED AROMATIC COMPOUNDS | CREO INGREDIENTS, INC. | 2023-11-23 | — | — | US | claimed |
| US-11685908-B2 | Prenyltransferase variants and methods for production of prenylated aromatic compounds | GENOMATICA, INC. (US) | 2023-06-27 | — | — | US | claimed |
| US-20220411766-A1 | COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ORTHOLOGOUS ENZYMES | RENEW BIOPHARMA INC (US) | 2022-12-29 | — | — | US | claimed |
| US-20220362320-A1 | METHODS FOR PREPARING EXTRACTS FROM PLANTS AND FUNGI | CANNA STREAM SOLUTIONS LTD. (CA) | 2022-11-17 | — | — | US | claimed |
| US-20220273585-A1 | Composition comprising at least one natural or synthetic non-euphoric cannabinoid and its method of manufacture | TILMAN (BE) | 2022-09-01 | — | — | US | claimed |
| EP-4049654-A1 | COMPOSITION COMPRISING AT LEAST ONE NATURAL OR SYNTHETIC CANNABINOID WITHOUT EUPHORIC EFFECT AND MANUFACTURING METHOD THEREOF | Eleonor (BE) | 2022-08-31 | — | — | EP | claimed |
| EP-4025705-A2 | PRENYLTRANSFERASE VARIANTS AND METHODS FOR PRODUCTION OF PRENYLATED AROMATIC COMPOUNDS | Genomatica, Inc. (US) | 2022-07-13 | — | — | EP | claimed |
| US-20230374473-A1 | PRENYLTRANSFERASE VARIANTS AND METHODS FOR PRODUCTION OF PRENYLATED AROMATIC COMPOUNDS | CREO INGREDIENTS, INC. | 2023-11-23 | — | — | US | disclosed |
| US-11685908-B2 | Prenyltransferase variants and methods for production of prenylated aromatic compounds | GENOMATICA, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20220411766-A1 | COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ORTHOLOGOUS ENZYMES | RENEW BIOPHARMA INC (US) | 2022-12-29 | — | — | US | disclosed |
| US-20220362320-A1 | METHODS FOR PREPARING EXTRACTS FROM PLANTS AND FUNGI | CANNA STREAM SOLUTIONS LTD. (CA) | 2022-11-17 | — | — | US | disclosed |
| US-20220347192-A1 | PRENYLTRANSFERASE VARIANTS AND METHODS FOR PRODUCTION OF PRENYLATED AROMATIC COMPOUNDS | CREO INGREDIENTS, INC. | 2022-11-03 | — | — | US | disclosed |
| US-20220273585-A1 | Composition comprising at least one natural or synthetic non-euphoric cannabinoid and its method of manufacture | TILMAN (BE) | 2022-09-01 | — | — | US | disclosed |
| EP-4049654-A1 | COMPOSITION COMPRISING AT LEAST ONE NATURAL OR SYNTHETIC CANNABINOID WITHOUT EUPHORIC EFFECT AND MANUFACTURING METHOD THEREOF | Eleonor (BE) | 2022-08-31 | — | — | EP | disclosed |
| EP-4025705-A2 | PRENYLTRANSFERASE VARIANTS AND METHODS FOR PRODUCTION OF PRENYLATED AROMATIC COMPOUNDS | Genomatica, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220273585-A1 | Composition comprising at least one natural or synthetic non-euphoric cannabinoid and its method of manufacture | CNR2, CNR1, FAAH | APP 681/4885BACE1 1739/4885PTPN1 2037/4885 |
| US-20220347192-A1 | PRENYLTRANSFERASE VARIANTS AND METHODS FOR PRODUCTION OF PRENYLATED AROMATIC COMPOUNDS | FNTA, COASY, PCYT1A | APP 882/4885BACE1 1294/4885PTPN1 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.