Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRK3 | P35626 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23167160 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL23167159 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL19916256 | 0.87 | ADRB2 (0.50) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL19897549 | 0.87 | ADRB2 (0.50) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL29772005 | 0.85 | TDP1 (0.51) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL23167452 | 0.85 | TDP1 (0.51) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL23167454 | 0.85 | TDP1 (0.51) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL19897526 | 0.82 | ADRB2 (0.46) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL19897525 | 0.82 | ADRB2 (0.46) | ALDH1A1KDM4EKMT2AADRB2TDP1 | |
| SCHEMBL23208146 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2ATDP1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037776-A1 | COMPOUNDS USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2022-08-10 | — | — | EP | disclosed |
| CN-114761085-A | Compounds useful as immunomodulators | 百时美施贵宝公司 | 2022-07-15 | — | — | CN | disclosed |