Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670434 | 0.86 | MAPT (0.69) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL753207 | 0.84 | MAPT (0.65) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL4635268 | 0.81 | MAPT (0.61) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL1100560 | 0.81 | MAPT (0.65) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL21464265 | 0.81 | MAPT (0.65) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL1100600 | 0.81 | MAPT (0.65) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL30615503 | 0.81 | MAPT (0.65) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL18053983 | 0.80 | ALDH1A1 (0.63) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL23117813 | 0.79 | MAPT (0.66) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL22466103 | 0.78 | MAPT (0.66) | MAPTALDH1A1LMNAALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853846-A | Androgen receptor degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2022-08-05 | — | — | CN | disclosed |