Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 15/20 | 0.65 |
| ▸ | METTL3 | Q86U44 | 14/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273897 | 1.00 | PRMT5 (0.65) | PRMT5METTL3 | |
| SCHEMBL23273773 | 0.91 | METTL3 (0.57) | PRMT5METTL3 | |
| SCHEMBL29772306 | 0.91 | METTL3 (0.57) | PRMT5METTL3 | |
| SCHEMBL25015460 | 0.87 | METTL3 (0.47) | PRMT5METTL3 | |
| SCHEMBL29772276 | 0.85 | PRMT5 (0.55) | PRMT5METTL3 | |
| SCHEMBL23313202 | 0.85 | PRMT5 (0.55) | PRMT5METTL3 | |
| SCHEMBL29772303 | 0.81 | METTL3 (0.57) | PRMT5METTL3 | |
| SCHEMBL23273890 | 0.81 | METTL3 (0.57) | PRMT5METTL3 | |
| SCHEMBL29772293 | 0.81 | METTL3 (0.57) | PRMT5METTL3 | |
| SCHEMBL23273756 | 0.79 | METTL3 (0.46) | PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048674-A2 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |