Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 18/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 17/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772303 | 1.00 | METTL3 (0.57) | METTL3PRMT5 | |
| SCHEMBL23273890 | 1.00 | METTL3 (0.57) | METTL3PRMT5 | |
| SCHEMBL29772306 | 0.90 | METTL3 (0.57) | METTL3PRMT5 | |
| SCHEMBL23273773 | 0.90 | METTL3 (0.57) | METTL3PRMT5 | |
| SCHEMBL29772256 | 0.81 | PRMT5 (0.65) | METTL3PRMT5 | |
| SCHEMBL23273897 | 0.81 | PRMT5 (0.65) | METTL3PRMT5 | |
| SCHEMBL25015460 | 0.80 | METTL3 (0.47) | METTL3PRMT5 | |
| SCHEMBL23273975 | 0.78 | METTL3 (0.56) | METTL3 | |
| SCHEMBL29805341 | 0.78 | METTL3 (0.56) | METTL3 | |
| SCHEMBL23273743 | 0.73 | METTL3 (1.00) | METTL3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048674-A2 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |