Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 13/20 | 0.77 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.41 |
| ▸ | ABL2 | P42684 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350731 | 0.87 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL22477572 | 0.87 | TGFBR1 (0.79) | TGFBR1MAPK14 | |
| SCHEMBL142081 | 0.87 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL21234477 | 0.85 | TGFBR1 (0.80) | TGFBR1MAPK14 | |
| SCHEMBL23091679 | 0.82 | TGFBR1 (0.64) | TGFBR1MAPK14GRM4ADORA3 | |
| SCHEMBL15452481 | 0.76 | TGFBR1 (0.55) | TGFBR1MAPK14THRBTGFBR2ABL2 | |
| SCHEMBL15452451 | 0.76 | TGFBR1 (0.55) | TGFBR1MAPK14THRBTGFBR2ABL2 | |
| SCHEMBL2045872 | 0.74 | TGFBR1 (0.68) | TGFBR1MAPK14THRBTGFBR2ABL2 | |
| SCHEMBL3247895 | 0.74 | TGFBR1 (0.68) | TGFBR1MAPK14THRBTGFBR2ABL2 | |
| SCHEMBL5278449 | 0.74 | TGFBR1 (0.67) | TGFBR1MAPK14THRBTGFBR2ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149615-A1 | CULTURE MEDIUM FOR EXPANSION CULTURE OF NEPHRON PROGENITOR CELL, METHOD FOR PERFORMING EXPANSION CULTURE OF NEPHRON PROGENITOR CELL, AND METHOD FOR PRODUCING KIDNEY ORGANOID | 国立大学法人京都大学 | 2022-07-14 | — | — | WO | disclosed |