Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 5/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23225714 | 0.76 | OPRM1 (0.48) | OPRM1MPO | |
| SCHEMBL27103572 | 0.76 | OPRM1 (0.32) | OPRM1MPOALDH1A1KDM4EMAPT | |
| SCHEMBL23225676 | 0.75 | MPO (0.42) | OPRM1MPOALDH1A1KDM4EGLA | |
| SCHEMBL23218012 | 0.74 | MPO (0.55) | OPRM1MPOALDH1A1GAAPLK1 | |
| SCHEMBL23225621 | 0.74 | MPO (0.55) | OPRM1MPOALDH1A1PLK1 | |
| SCHEMBL27102076 | 0.74 | KDM4E (0.31) | KDM4EGAA | |
| SCHEMBL27103046 | 0.71 | MPO (0.54) | OPRM1MPOALDH1A1GAA | |
| SCHEMBL23217931 | 0.71 | OPRM1 (0.40) | OPRM1MPOALDH1A1KDM4EGLA | |
| SCHEMBL27102078 | 0.67 | MPO (0.45) | OPRM1MPOALDH1A1KDM4EMAPT | |
| SCHEMBL29211240 | 0.64 | MPO (0.52) | OPRM1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041735-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | Biohaven Therapeutics Ltd. (US) | 2022-08-17 | — | — | EP | disclosed |