Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | NNMT | P40261 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901086 | 1.00 | TDP1 (0.68) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL9649585 | 0.89 | TDP1 (0.64) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL23650002 | 0.84 | TDP1 (0.58) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL23650005 | 0.84 | TDP1 (0.58) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL9236131 | 0.81 | TDP1 (0.46) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL5583783 | 0.81 | TDP1 (0.53) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL3780312 | 0.81 | TDP1 (0.53) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL838850 | 0.81 | NNMT (0.71) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL1279306 | 0.81 | TDP1 (0.53) | TDP1POLBNNMTALDH1A1KDM4E | |
| SCHEMBL7540568 | 0.81 | TDP1 (0.68) | TDP1POLBNNMTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545757-A | 5-oxo-pyrido [2,3-d ] pyridazin-6 (5H) -ylacetamides | 詹森药业有限公司 | 2024-02-09 | — | — | CN | disclosed |
| WO-2022138636-A1 | METAL COMPLEX OR ADDUCT THEREOF, CATALYST COMPRISING METAL COMPLEX OR ADDUCT THEREOF AND METHOD FOR PRODUCING SAME, LIQUID COMPOSITION OR ELECTRODE CONTAINING CATALYST, AND AIR BATTERY OR FUEL CELL EQUIPPED WITH ELECTRODE | ＡＺＵＬ Ｅｎｅｒｇｙ株式会社 | 2022-06-30 | — | — | WO | disclosed |