Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | NNMT | P40261 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040184 | 0.83 | TDP1 (0.66) | TDP1POLBNNMTMAPTSORT1 | |
| SCHEMBL29859234 | 0.81 | TDP1 (1.00) | TDP1POLBNNMTMAPTSORT1 | |
| SCHEMBL7901086 | 0.81 | TDP1 (0.68) | TDP1POLBNNMTMAPTSORT1 | |
| SCHEMBL29774201 | 0.81 | TDP1 (0.68) | TDP1POLBNNMTMAPTSORT1 | |
| SCHEMBL198490 | 0.81 | TDP1 (1.00) | TDP1POLBNNMTMAPTSORT1 | |
| SCHEMBL838850 | 0.81 | NNMT (0.71) | TDP1POLBNNMTMAPTSORT1 | |
| SCHEMBL21339634 | 0.79 | TDP1 (0.66) | TDP1POLBNNMTMAPTSORT1 | |
| SCHEMBL30940155 | 0.79 | TDP1 (0.66) | TDP1POLBNNMTMAPTSORT1 | |
| Hydrochloric Acid SCHEMBL10988320 | 0.79 | TDP1 (0.96) | TDP1POLBNNMTMAPTSORT1 | |
| SCHEMBL1300585 | 0.79 | TDP1 (0.66) | TDP1POLBNNMTMAPTSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002029021-A2 | BIOTECHNOLOGICAL METHOD FOR PREPARING CARBOXYLIC ACIDS WITH A HYDROXY-NITROGEN HETEROCYCLE | LONZA AG (CH) | 2002-04-11 | — | — | WO | disclosed |