Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSH | P09668 | 1/20 | 0.48 |
| ▸ | GLP1R | P43220 | 5/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | GRPR | P30550 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484310 | 0.92 | CTSL (0.53) | IL23RCTSLCTSSCTSKCTSH | |
| SCHEMBL29740507 | 0.90 | IL23R (0.48) | IL23RCTSLCTSSCTSKCTSH | |
| SCHEMBL30951030 | 0.90 | CTSL (0.47) | IL23RCTSLCTSSCTSKCTSH | |
| SCHEMBL30183034 | 0.90 | GLP1R (0.55) | IL23RCTSLCTSSCTSKCTSH | |
| SCHEMBL30354997 | 0.88 | GRPR (0.47) | IL23RCTSLCTSSCTSKCTSH | |
| SCHEMBL29519330 | 0.87 | CTSL (0.57) | CTSLCTSSCTSKCTSHGLP1R | |
| SCHEMBL30064553 | 0.87 | GLP1R (0.58) | IL23RGLP1RGRPR | |
| SCHEMBL29489380 | 0.86 | CTSL (0.53) | IL23RCTSLCTSSCTSKCTSH | |
| SCHEMBL30338573 | 0.86 | GLP1R (0.54) | IL23RCTSLCTSSCTSKCTSH | |
| SCHEMBL30932143 | 0.85 | GLP1R (0.60) | GLP1RCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022178594-A1 | C-REACTIVE PROTEIN INHIBITORS | Baker Heart and Diabetes Institute (AU) | 2022-09-01 | — | — | WO | disclosed |