SCHEMBL30338573

SCHEMBL30338573

C[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@H](C(N)=O)[C@@H](C)O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 4/20 0.54
▸ GRPR P30550 1/20 0.54
▸ KEAP1 Q14145 1/20 0.53
▸ NR3C1 P04150 2/20 0.53
▸ IL23R Q5VWK5 8/20 0.53
▸ GCGR P47871 1/20 0.53
▸ CXCR4 P61073 1/20 0.52
▸ CTSL P07711 1/20 0.52
▸ CTSH P09668 1/20 0.52
▸ CTSS P25774 1/20 0.52
▸ CTSK P43235 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484311 0.97 GLP1R (0.56) GLP1RGRPRKEAP1NR3C1IL23R
SCHEMBL29484320 0.95 IL23R (0.53) GLP1RGRPRKEAP1IL23RGCGR
SCHEMBL30208638 0.94 GLP1R (0.57) GLP1RIL23RGCGRCXCR4
SCHEMBL29484310 0.94 CTSL (0.53) GLP1RGRPRKEAP1IL23RCXCR4
SCHEMBL29484313 0.93 NPBWR1 (0.55) GLP1RGRPRKEAP1NR3C1IL23R
SCHEMBL31119241 0.92 IL23R (0.53) GLP1RGRPRKEAP1NR3C1IL23R
SCHEMBL30388309 0.92 IL23R (0.53) GLP1RGRPRKEAP1IL23RCXCR4
SCHEMBL30208639 0.91 GLP1R (0.60) GLP1RIL23RGCGRCXCR4
SCHEMBL30183034 0.91 GLP1R (0.55) GLP1RGRPRIL23RCXCR4CTSL
SCHEMBL29670416 0.90 CTSL (0.50) GLP1RGRPRIL23RCXCR4CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528836-B2 Dosing regimens APELLIS PHARMACEUTICALS, INC. (US) 2026-01-20 — — US disclosed
US-20250282823-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND RELATED COMPOSITIONS AND METHODS APELLIS PHARMACEUTICALS, INC. 2025-09-11 — — US disclosed
US-20240285725-A1 DOSING REGIMENS SIXTH STREET LENDING PARTNERS 2024-08-29 — — US disclosed
US-11903994-B2 Dosing regimens APELLIS PHARMACEUTICALS, INC. (US) 2024-02-20 — — US disclosed
US-20230091471-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND RELATED COMPOSITIONS AND METHODS SIXTH STREET LENDING PARTNERS 2023-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11903994-B2 Dosing regimens C3AR1, C1QBP, C9 GLP1R 320/4885GRPR 383/4885KEAP1 547/4885
US-20240285725-A1 DOSING REGIMENS C3AR1, C1QBP, C9 GLP1R 320/4885GRPR 383/4885KEAP1 547/4885
US-20250282823-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND RELATED COMPOSITIONS AND METHODS C3AR1, C9, C1QBP GLP1R 279/4885GRPR 377/4885KEAP1 1149/4885
US-20230091471-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND RELATED COMPOSITIONS AND METHODS C3AR1, C9, C1QBP GLP1R 283/4885GRPR 377/4885KEAP1 1147/4885
US-12528836-B2 Dosing regimens CFD, CFB, VIP GLP1R 320/4885GRPR 357/4885KEAP1 3286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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