SCHEMBL29774696

SCHEMBL29774696

C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.53
▸ NPY1R P25929 4/20 0.52
▸ NPY2R P49146 1/20 0.52
▸ NPY4R P50391 1/20 0.52
▸ CYP1A2 P05177 1/20 0.47
▸ GLA P06280 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ NFKB1 P19838 1/20 0.47
▸ APEX1 P27695 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ NOS2 P35228 1/20 0.47
▸ NRP1 O14786 2/20 0.47
▸ NPY5R Q15761 2/20 0.47
▸ FURIN P09958 5/20 0.46
▸ EED O75530 1/20 0.45
▸ SIRT5 Q9NXA8 2/20 0.45
▸ SIRT2 Q8IXJ6 1/20 0.45
▸ GNPAT O15228 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29774670 1.00 EGFR (0.53) EGFRNPY1RNPY2RNPY4RCYP1A2
SCHEMBL1738251 0.95 CYP2C19 (0.51) EGFRNPY1RNPY2RNPY4RCYP1A2
SCHEMBL1735294 0.94 NPY1R (0.55) EGFRNPY1RNPY2RNPY4RCYP1A2
SCHEMBL29774695 0.93 EGFR (0.60) EGFRNPY1RNPY2RNPY4RCYP1A2
SCHEMBL1736266 0.87 NPY1R (0.55) EGFRNPY1RNPY2RNPY4RCYP1A2
SCHEMBL29794337 0.86 CYP2C19 (0.56) EGFRNPY1RNPY2RNPY4RCYP1A2
SCHEMBL30296822 0.86 NOS2 (0.63) NPY1RNPY2RNPY4RCYP1A2GLA
SCHEMBL29354613 0.85 TERT (0.48) EGFRNPY1RNPY2RNPY4RCYP1A2
SCHEMBL29351042 0.84 ERAP2 (0.52) EGFRNPY1RNPY2RNPY4RCYP1A2
SCHEMBL29355798 0.84 NPY1R (0.51) EGFRNPY1RNPY2RNPY4RCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3777875-B1 SURGICAL METHODS EMPLOYING PURIFIED AMPHIPHILIC PEPTIDE COMPOSITIONS 3 D MATRIX LTD (JP) 2025-12-03 — — EP disclosed
EP-3548105-B1 METHOD FOR PRODUCING A PEPTIDE-BASED NANO FIBER STRUCTURE AND A NANO FIBER STRUCTURE THUS OBTAINED HUMANA MEDICAL S R L (IT) 2025-03-05 — — EP disclosed
US-12006085-B2 Fill-finish process for peptide solutions 3-D MATRIX, LTD. (JP) 2024-06-11 — — US disclosed
US-11839694-B2 Compositions and methods for promoting hemostasis and other physiological activities MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-12-12 — — US disclosed
US-20230190864-A1 PURIFIED AMPHIPHILIC PEPTIDE COMPOSITIONS AND USES THEREOF 3-D MATRIX, LTD. (JP) 2023-06-22 — — US disclosed
EP-2283851-B1 Compositions for promoting hemostasis MASSACHUSETTS INST TECHNOLOGY (US) 2023-06-07 — — EP disclosed
US-20220324601-A1 FILL-FINISH PROCESS FOR PEPTIDE SOLUTIONS 3-D MATRIX, LTD. (JP) 2022-10-13 — — US disclosed
EP-4049671-A1 PURIFIED AMPHIPHILIC PEPTIDE COMPOSITIONS AND USES THEREOF 3D Matrix, Inc. (US) 2022-08-31 — — EP disclosed
US-20220258900-A9 FILL-FINISH PROCESS FOR PEPTIDE SOLUTIONS 3-D MATRIX, LTD. (JP) 2022-08-18 — — US disclosed
EP-4023240-A1 PURIFIED AMPHIPHILIC PEPTIDE COMPOSITIONS AND USES THEREOF 3D Matrix, Inc. (US) 2022-07-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190864-A1 PURIFIED AMPHIPHILIC PEPTIDE COMPOSITIONS AND USES THEREOF IAPP, NGLY1, VIP EGFR 1852/4885NPY1R 3582/4885NPY2R 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback