SCHEMBL29776898

SCHEMBL29776898

[N-]=[N+]=NCO[C@H]1C[C@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)O[C@@H]1CO

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ P2RY12 Q9H244 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ ADORA1 P30542 2/20 0.42
▸ P2RY2 P41231 1/20 0.42
▸ P2RY1 P47900 1/20 0.42
▸ P2RY6 Q15077 1/20 0.42
▸ SLC29A1 Q99808 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31629565 0.85 POLB (0.49) POLBADORA1SLC29A1
SCHEMBL29514600 0.85 KDM4E (0.56) POLBADORA1SLC29A1
SCHEMBL15143709 0.85 POLB (0.61) POLBADORA1SLC29A1
SCHEMBL19519648 0.85 POLB (0.61) POLBADORA1SLC29A1
SCHEMBL11683614 0.85 POLB (0.61) POLBADORA1SLC29A1
SCHEMBL12362206 0.85 POLB (0.61) POLBADORA1SLC29A1
SCHEMBL4727394 0.84 ADORA1 (0.46) POLBADORA1SLC29A1
SCHEMBL4727404 0.84 ADORA1 (0.46) POLBADORA1SLC29A1
SCHEMBL11049246 0.84 POLB (0.51) POLBADORA1SLC29A1
SCHEMBL20534948 0.84 POLB (0.51) POLBADORA1SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12227798-B2 Methods and compositions for incorporating nucleotides IsoPlexis Corporation (US) 2025-02-18 — — US disclosed
US-20250052717-A1 METHODS AND DEVICES FOR SEQUENCING NUCLEIC ACIDS IN SMALLER BATCHES QIAGEN SCIENCES, LLC 2025-02-13 — — US disclosed
US-11940413-B2 Methods and devices for sequencing nucleic acids in smaller batches IsoPlexis Corporation (US) 2024-03-26 — — US disclosed
US-20240076731-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES QIAGEN SCIENCES, LLC 2024-03-07 — — US disclosed
US-20240060128-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES QIAGEN WALTHAM, INC. 2024-02-22 — — US disclosed
US-20230407384-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES QIAGEN WALTHAM, INC. 2023-12-21 — — US disclosed
EP-4162035-A2 MODIFIED TEMPLATE-INDEPENDENT ENZYMES FOR POLYDEOXYNUCLEOTIDE SYNTHESIS Molecular Assemblies Inc. (US) 2023-04-12 — — EP disclosed
US-11390858-B2 Modified template-independent enzymes for polydeoxynucleotide synthesis Molecular Assemblies, Inc. (US) 2022-07-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12227798-B2 Methods and compositions for incorporating nucleotides NT5C2, NOP2, NT5C3B P2RY12 387/4885POLB 44/4885ADORA1 488/4885
US-20240076731-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES NT5C2, NOP2, NT5C3B P2RY12 387/4885POLB 44/4885ADORA1 488/4885
US-20230407384-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES NT5C2, NOP2, NT5C3B P2RY12 387/4885POLB 44/4885ADORA1 488/4885
US-20240060128-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES NT5C2, NOP2, NT5C3B P2RY12 387/4885POLB 44/4885ADORA1 488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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