SCHEMBL2977700

SCHEMBL2977700

CCCC=C1CCC(NC(=O)O)CC1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
EPHX1 P07099 4/20 0.33
MTNR1A P48039 2/20 0.33
MTNR1B P49286 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2978435 0.81
SCHEMBL17592404 0.78 TLR4 (0.39) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL16192233 0.70
SCHEMBL1950227 0.69 TLR4 (0.43) ALDH1A1MEN1KMT2AMTNR1AMTNR1B
SCHEMBL15939540 0.69 DRD3 (0.39) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL18876827 0.69 DRD3 (0.30)
SCHEMBL743138 0.68 EPHX1 (0.36) ALDH1A1MEN1KMT2AMAPTHPGD
Hydrochloric Acid SCHEMBL2975208 0.67 GNAI3 (0.32)
Acetic Acid SCHEMBL28266825 0.67 TLR4 (0.37) ALDH1A1MAPTHPGDEPHX1MTNR1A
SCHEMBL15751659 0.66 EPHX1 (0.34) ALDH1A1MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7767854-B2 N-substituted phenylacetamide derivative and pharmaceutical composition containing the same DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2010-08-03 US disclosed
US-20090082463-A1 N-substituted phenylacetamide derivative and pharmaceutical composition containing the same DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2009-03-26 US disclosed
EP-1884510-A1 N-SUBSTITUTED PHENYLACETAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Dainippon Sumitomo Pharma Co., Ltd. (JP) 2008-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090082463-A1 N-substituted phenylacetamide derivative and pharmaceutical composition containing the same HRH4, HRH2, CNR2 ALDH1A1 321/4885MEN1 3895/4885KMT2A 1935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.