⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977700 | 0.81 | ALDH1A1 (0.34) | — | |
| SCHEMBL17592404 | 0.72 | TLR4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL2962683 | 0.69 | — | — | |
| SCHEMBL850863 | 0.68 | PLG (0.38) | — | |
| SCHEMBL15939540 | 0.67 | DRD3 (0.39) | — | |
| SCHEMBL743138 | 0.66 | EPHX1 (0.36) | — | |
| SCHEMBL15751659 | 0.64 | EPHX1 (0.34) | — | |
| SCHEMBL245467 | 0.64 | — | — | |
| SCHEMBL6658887 | 0.64 | EPHX2 (0.50) | — | |
| SCHEMBL22191220 | 0.64 | SMYD3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767854-B2 | N-substituted phenylacetamide derivative and pharmaceutical composition containing the same | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090082463-A1 | N-substituted phenylacetamide derivative and pharmaceutical composition containing the same | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1884510-A1 | N-SUBSTITUTED PHENYLACETAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-02-06 | — | — | EP | disclosed |