Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 6/20 | 0.56 |
| ▸ | NMUR1 | Q9HB89 | 6/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 5/20 | 0.50 |
| ▸ | RAMP3 | O60896 | 4/20 | 0.50 |
| ▸ | CALCR | P30988 | 4/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678863 | 0.87 | NMUR2 (0.56) | NMUR2NMUR1OPRM1OPRK1REN | |
| SCHEMBL30495598 | 0.87 | NMUR2 (0.49) | NMUR2NMUR1EPHA2OPRM1OPRK1 | |
| SCHEMBL30011888 | 0.85 | OPRM1 (0.55) | NMUR2NMUR1KEAP1OPRM1OPRK1 | |
| SCHEMBL30288848 | 0.85 | NMUR2 (0.58) | NMUR2NMUR1MAPK8MAPK9MAPK10 | |
| SCHEMBL30932611 | 0.85 | EPHA2 (0.59) | NMUR2NMUR1EPHA2MAPK8MAPK9 | |
| SCHEMBL31433412 | 0.84 | APLNR (0.58) | NMUR2NMUR1MAPK8MAPK9MAPK10 | |
| SCHEMBL30629127 | 0.84 | NMUR2 (0.63) | NMUR2NMUR1KEAP1OPRM1OPRK1 | |
| SCHEMBL30930553 | 0.84 | NMUR2 (0.67) | NMUR2NMUR1KEAP1EPHA2RAMP3 | |
| SCHEMBL31356488 | 0.84 | EPHA2 (0.58) | NMUR2NMUR1KEAP1EPHA2OPRM1 | |
| SCHEMBL31106633 | 0.84 | MAPK8 (0.59) | NMUR2NMUR1KEAP1EPHA2RAMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4591934-A2 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4523749-A2 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-4029512-A1 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2022-07-20 | — | — | EP | disclosed |