Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454078 | 0.85 | TDP1 (0.47) | GAAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL29777619 | 0.83 | GAA (0.46) | GAAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7456718 | 0.83 | HPGD (0.45) | GAAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28260851 | 0.82 | SMN1; SMN2 (0.41) | GAAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8036125 | 0.80 | CYP2C9 (0.64) | GAAMEN1KMT2AHPGDCYP2C9 | |
| SCHEMBL29777618 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7457590 | 0.79 | HPGD (0.46) | GAAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL4096910 | 0.74 | ALDH1A1 (0.46) | GAAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL12800195 | 0.74 | TDP1 (0.46) | GAAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL12725198 | 0.72 | TDP1 (0.44) | GAAMEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948019-B | Focal adhesion kinase inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |