Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100810 | 0.90 | UCHL1 (0.49) | ALDH1A1HPGDL3MBTL1TDP1UCHL1 | |
| SCHEMBL17458955 | 0.79 | DCTPP1 (0.51) | UCHL1NPBWR1SMN1; SMN2MAPTDCTPP1 | |
| SCHEMBL14801244 | 0.79 | NPBWR1 (0.53) | NPBWR1SMN1; SMN2MAPTDCTPP1 | |
| SCHEMBL7454078 | 0.78 | TDP1 (0.47) | ALDH1A1HPGDTDP1PKMSMN1; SMN2 | |
| SCHEMBL17458864 | 0.78 | LMNA (0.47) | ALDH1A1L3MBTL1TDP1PKMSMN1; SMN2 | |
| SCHEMBL14052805 | 0.77 | GAA (0.55) | ALDH1A1TDP1PKMSMN1; SMN2GAA | |
| SCHEMBL17459012 | 0.75 | CYP11B1 (0.51) | ALDH1A1HPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL29777571 | 0.74 | GAA (0.45) | ALDH1A1HPGDTDP1PKMSMN1; SMN2 | |
| SCHEMBL3287293 | 0.73 | DCTPP1 (0.58) | HPGDNPBWR1PKMSMN1; SMN2MAPT | |
| SCHEMBL7457590 | 0.72 | HPGD (0.46) | ALDH1A1HPGDPKMSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1903045-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MC2R, CRHR1, AVPR2 | ALDH1A1 1328/4885HPGD 1017/4885L3MBTL1 4477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.