SCHEMBL29777638

SCHEMBL29777638

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 5/20 0.47
▸ F2 P00734 3/20 0.45
▸ PRCP P42785 1/20 0.43
▸ OPRM1 P35372 1/20 0.42
▸ NTMT1 Q9BV86 1/20 0.42
▸ STAT6 P42226 1/20 0.41
▸ TLR2 O60603 2/20 0.41
▸ CMA1 P23946 1/20 0.41
▸ LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777748 0.97 ACE (0.45) ACEF2PRCPOPRM1NTMT1
SCHEMBL29777663 0.94 PRCP (0.48) ACEF2PRCPOPRM1TLR2
SCHEMBL29777648 0.94 ACE (0.49) ACEF2PRCPOPRM1NTMT1
SCHEMBL29750784 0.91 ACE (0.45) ACEF2PRCPOPRM1NTMT1
SCHEMBL29566581 0.88 CTRB1 (0.46) ACEF2PRCP
SCHEMBL31500760 0.85 PRCP (0.51) ACEF2PRCPOPRM1STAT6
SCHEMBL29413336 0.84 CTRB1 (0.49) F2LMNA
SCHEMBL30317756 0.84 CTRB1 (0.49) F2LMNA
SCHEMBL8902510 0.84 CTRB1 (0.49) F2LMNA
SCHEMBL31297111 0.84 TLR2 (0.46) F2PRCPNTMT1TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989313-B P-tau181 epitope peptide and application thereof in Alzheimer disease detection 福建亿彤生物科技有限公司 2024-04-02 — — CN claimed
CN-114989313-A P-tau181 epitope peptide and application thereof in Alzheimer disease detection 亿彤科技发展(福建)有限公司 2022-09-02 — — CN claimed
CN-114989313-B P-tau181 epitope peptide and application thereof in Alzheimer disease detection 福建亿彤生物科技有限公司 2024-04-02 — — CN disclosed
CN-114989313-A P-tau181 epitope peptide and application thereof in Alzheimer disease detection 亿彤科技发展(福建)有限公司 2022-09-02 — — CN disclosed
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