SCHEMBL29777663

SCHEMBL29777663

C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 1/20 0.48
▸ ACE P12821 3/20 0.47
▸ TLR2 O60603 2/20 0.46
▸ F2 P00734 3/20 0.45
▸ FDFT1 P37268 1/20 0.45
▸ MDM2 Q00987 4/20 0.44
▸ DPP4 P27487 1/20 0.43
▸ DPP8 Q6V1X1 1/20 0.43
▸ CMA1 P23946 1/20 0.42
▸ OPRM1 P35372 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777638 0.94 ACE (0.47) PRCPACETLR2F2CMA1
SCHEMBL29777748 0.91 ACE (0.45) PRCPACETLR2F2OPRM1
SCHEMBL31500760 0.90 PRCP (0.51) PRCPACETLR2F2FDFT1
SCHEMBL31297111 0.90 TLR2 (0.46) PRCPTLR2F2FDFT1MDM2
SCHEMBL29777648 0.89 ACE (0.49) PRCPACETLR2F2FDFT1
SCHEMBL31297113 0.87 F2 (0.47) PRCPACETLR2F2FDFT1
SCHEMBL29750784 0.86 ACE (0.45) PRCPACETLR2F2FDFT1
SCHEMBL31297115 0.84 APLNR (0.45) TLR2FDFT1OPRM1
SCHEMBL31500752 0.84 CMA1 (0.45) PRCPCMA1
SCHEMBL17015151 0.83 ACE (0.52) PRCPACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989313-B P-tau181 epitope peptide and application thereof in Alzheimer disease detection 福建亿彤生物科技有限公司 2024-04-02 — — CN claimed
CN-114989313-A P-tau181 epitope peptide and application thereof in Alzheimer disease detection 亿彤科技发展(福建)有限公司 2022-09-02 — — CN claimed
CN-114989313-B P-tau181 epitope peptide and application thereof in Alzheimer disease detection 福建亿彤生物科技有限公司 2024-04-02 — — CN disclosed
CN-114989313-A P-tau181 epitope peptide and application thereof in Alzheimer disease detection 亿彤科技发展(福建)有限公司 2022-09-02 — — CN disclosed
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