SCHEMBL29777968

SCHEMBL29777968

C[C@@H](N)[C@](C)(CN)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRA3 P34903 2/20 0.34
GABRA2 P47869 2/20 0.34
GABRB2 P47870 2/20 0.34
GABRA4 P48169 2/20 0.34
GABRE P78334 2/20 0.34
GABRA6 Q16445 2/20 0.34
GABRG1 Q8N1C3 2/20 0.34
GABRG3 Q99928 2/20 0.34
GABRQ Q9UN88 2/20 0.34
GABRR1 P24046 2/20 0.34
ALDH1A1 P00352 2/20 0.34
SLC7A5 Q01650 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803930 0.74 TSHR (0.35) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL3794658 0.70 KDM4E (0.41) KDM4EGABRPGABRDGABRA1GABRB1
SCHEMBL18824851 0.69
SCHEMBL466827 0.69
SCHEMBL7353061 0.69 ALDH1A1 (0.40) GABRPGABRDGABRA1GABRB1GABRG2
Hydrochloric Acid SCHEMBL2677291 0.68 KDM4E (0.44) KDM4EGABRR1ALDH1A1MAPTPTGS1
Iodide SCHEMBL10424820 0.68 KDM4E (0.39) KDM4EGABRPGABRDGABRA1GABRB1
SCHEMBL5478250 0.68 ALDH1A1 (0.32) KDM4EALDH1A1MAPTPTGS1TSHR
Hydrochloric Acid SCHEMBL3507710 0.67 ALDH1A1 (0.39) KDM4EGABRPGABRDGABRA1GABRB1
Water SCHEMBL7767504 0.67 ALDH1A1 (0.39) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106811491-B Preparation method of optically active beta-hydroxy ester compound and intermediate thereof 焦作健康元生物制品有限公司 2022-07-19 CN disclosed