Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778709 | 0.88 | GAA (0.59) | GAATHRBTSHRMEN1POLB | |
| SCHEMBL29778725 | 0.87 | SCN4A (0.51) | GAATSHRPOLBSMN1; SMN2DCUN1D1 | |
| Hydrochloric Acid SCHEMBL7810311 | 0.81 | KMT2A (0.58) | POLBKMT2AALDH1A1 | |
| SCHEMBL6750641 | 0.75 | OPRM1 (0.54) | ALDH1A1CYP2D6 | |
| SCHEMBL29778727 | 0.75 | SCN4A (0.50) | GAATSHRPOLBSMN1; SMN2DCUN1D1 | |
| Hydrochloric Acid SCHEMBL3156656 | 0.75 | ABL1 (0.56) | TSHRMEN1KMT2A | |
| SCHEMBL7810400 | 0.75 | ABL1 (0.56) | TSHRMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29778740 | 0.74 | GAA (0.54) | GAATHRBTSHRMEN1POLB | |
| SCHEMBL26096557 | 0.74 | ABL1 (0.54) | GAATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2191304 | 0.70 | GAA (0.55) | GAATHRBMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763335-B | 4-Amide piperidine derivative and preparation method and application thereof | 江苏谛奇医药科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-114763335-A | 4-amide piperidine derivative and preparation method and application thereof | 江苏谛奇医药科技有限公司 | 2022-07-19 | — | — | CN | disclosed |