Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778799 | 0.89 | LMNA (0.47) | GAASMN1; SMN2MAOBPOLBDCUN1D1 | |
| SCHEMBL29778730 | 0.86 | POLB (0.53) | GAASMN1; SMN2POLBKMT2ADCUN1D1 | |
| SCHEMBL29778764 | 0.84 | SCN4A (0.55) | SMN1; SMN2POLBMEN1KMT2ADCUN1D1 | |
| SCHEMBL29778716 | 0.82 | HDAC1 (0.52) | GAASMN1; SMN2MEN1KMT2AHDAC3 | |
| SCHEMBL29778721 | 0.79 | ATM (0.53) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL29778733 | 0.79 | KMT2A (0.54) | SMN1; SMN2TSHRMEN1KMT2AMAPT | |
| SCHEMBL29778731 | 0.78 | ALDH1A1 (0.60) | SMN1; SMN2POLBKMT2ADCUN1D1MAPT | |
| SCHEMBL29778717 | 0.78 | MAPT (0.56) | SMN1; SMN2KMT2ALMNAMAPTBCHE | |
| SCHEMBL29778752 | 0.74 | GAA (0.60) | GAATHRBSMN1; SMN2TSHRPOLB | |
| SCHEMBL29778709 | 0.73 | GAA (0.59) | GAATHRBSMN1; SMN2TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763335-B | 4-Amide piperidine derivative and preparation method and application thereof | 江苏谛奇医药科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-114763335-A | 4-amide piperidine derivative and preparation method and application thereof | 江苏谛奇医药科技有限公司 | 2022-07-19 | — | — | CN | disclosed |